Association Between Baseline Serum Ferritin and Short-term Outcome of Intracerebral Hemorrhage: A Meta-Analysis

Background: Intracerebral hemorrhage is a devastating disease. In recent years, the association of between baseline serum ferritin and prognosis of intracerebral hemorrhage is an interesting issue. Although some of the studies have shown that baseline serum ferritin can predict the prognosis of intracerebral hemorrhage, there is no clear evidence that baseline serum ferritin can be used as an independent predictor of intracerebral hemorrhage. Methods: Electronic databases through November 2018 were searched to identify relevant studies that examined association between baseline serum ferritin and prognosis of intracerebral hemorrhage. Results: We found 7 eligible studies that included 411 participants. Our results showed that among them, 216 patients with intracerebral hemorrhage of poorer functional outcome were associated with elevated serum ferritin at admission. The results of 7 literature meta-analysis showed that intracerebral hemorrhage (ICH) patients with favorable shot-term functional outcome had lower baseline serum ferritin levels, with significant mean differences of ?70.85 (95% confidence intervals ?134.26, ?7.43). Conclusions: This meta-analysis showed that baseline serum ferritin level at admission may predict the short-term prognosis of patients with ICH, and may provide a new target for intracerebral hemorrhage therapy.     

Correlation between the Xba I polymorphism of apoB gene and serum lipid profiles in Li ethnic group

ObjectiveTo study correlation between the Xba I polymorphism of apoB gene and plasma lipid profiles in Li ethnic group.MethodsTotal 151 cases of healthy Li people were recruited randomly by cluster sampling and 200 Han people were recruited as control; blood was drawn to analyze Xba I polymorphism distribution of apoB gene and serum lipid levels.ResultsThere were lower serum total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) levels in serum of Li people; while, high density lipoprotein cholesterol (HDL-C), X⁻/X⁺ genotype and X⁺ allele frequencies exhibited higher levels than Han people. Interestingly, HDL-C level was reduced, while LDL-C level was enhanced in subjects carrying heterozygous (X⁻/X⁺) genotype compared to homozygous (X⁻/X⁻) genotype. Additionally, there were no difference in serum level of triglyceride, TC, apoprotein A (apo A) and apoprotein B (apo B) between Li and Han people, the same results were showed between X⁻/X⁺ and X⁻/X⁻ genotype carriers.ConclusionsXba I polymorphism of apoB gene is correlated to the profiles of serum lipid level, X⁻/X⁺ genotype carriers are phenotyped with higher LDL-C level and lower level of HDL-C in Li ethnic group.     

黎族大学生积极/消极情感的性别差异

目的 探讨黎族大学生积极/消极情感的性别差异及其与人格特质、家庭环境的关系.方法 使用Bradburn的积极/消极情感量表、中国人人格量表(QZPS)和家庭环境量表中文版(FES-CV)对367名黎族大学生进行调查.结果 ①男生积极情感和情感平衡显著高于女生(t=4.01,4.07;P＜0.001);②男生积极情感与消极情感显著正相关(r=0.11,P＜0.05),而女生显著负相关(r=-0.10,P＜0.05);③男生情感平衡与人格善良、行事风格、才干、情绪性呈显著相关(r=-0.17,-0.18,0.16,0.18;P＜0.001),女生不显著;女生情感平衡与人格外向性呈显著相关(r=-0.16,P＜0.001),男生不显著;黎族大学生积极/消极情感与家庭环境各雏度的相关也呈显著性别差异.结论 黎族大学生积极/消极情感的性别差异在表现形式和社会心理成因方面具有一定的复杂性和特殊性.     

稳心颗粒治疗更年期心律失常的疗效观察

目的：观察稳心颗粒治疗更年期心律失常的疗效。方法：将79例更年期心律失常女性患者分为治疗组（n=37）和对照组（n=42）,对照组口服谷维素（10mg／次,3次／d）及维生素B．（10mg／;k,3次／d）,治疗组在对照组的基础上加服稳心颗粒（9g／）L,3次,d）,4周后观察两组的疗效,治疗前后两组都检查心电图、动态心电图、肝功能、肾功能、血常规、尿常规。结果：治疗组总有效率83．78％,对照组总有效率45．23％（X^2=7．659,P〈0．008）,差异显著;治疗组和对照组之间的不良反应无差异（x^2=0．877,P=0．463）。结论：稳心颗粒治疗更年期心律失常有较高的效率。     

阿德福韦酯治疗黎族CHB患者疗效与HBV基因型的关系

目的评价阿德福韦酯治疗黎族慢性乙型肝炎(CHB)患者疗效与乙型肝炎病毒(HBV)基因型的关系。方法 42例HBeAg阳性、HBVDNA>105copies/ml、ALT>2倍正常值上线的黎族CHB患者,每天口服阿德福韦酯胶囊10mg,治疗48周。在治疗前及治疗后48周,动态观察HBeAg、HBVDNA和ALT的变化。结果 42例患者中,HBVC型是优势基因型(57.14%),其次为B型(38.10%),也有D型(2.38%)和C+D型混合感染(2.38%)的存在。经阿德福韦酯胶囊治疗48周后,B型患者HBeAg阴转率(37.50%)、病毒应答率(56.25%)和血清ALT复常率(62.50%)均高于C型的29.17%、50.00%和54.17%,但两组比较差异无统计学意义(P>0.05)。结论 HBVC型是海南岛黎族HBeAg阳性CHB患者的优势基因型,HBV基因型可能对阿德福韦酯的治疗效果无影响。     

李东垣升阳法之研究概述

李东垣升阳法是东垣创立脾胃内伤学说基础上形成的独特治法,是东垣以脾胃为中心的学术思想在治法层面的突出表现,从古到今广泛的应用于临床各科。升阳法作为中医学术体系的重要部分,其理论滥觞于《黄帝内经》,治法肇始于仲景（《伤寒杂病论》,历经唐宋时期的探索和学术积淀,至金代李东垣《脾胃论》问世,升阳法的理论、具体治法和临床应用等,初成体系。